Immunology of the Schwann cell.

  title={Immunology of the Schwann cell.},
  author={Patricia J. Armati and John David Pollard},
  journal={Bailliere's clinical neurology},
  volume={5 1},
The Schwann cell or its myelin membrane appears to be the focus of autoimmune attack in several peripheral neuropathies. Potential Schwann cell antigens have therefore been extensively studied. Of the known Schwann cell proteins, MBP, P2, MAG, PLP, PO, PMP-22 and Connexin 32, gene defects of the latter three have recently been shown to be responsible for some forms of hereditary sensory and motor neuropathies. The L2/HNK-1 epitope, common to MAG, Po and PMP-22, is the target of autoantibody… CONTINUE READING
10 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…