Immunology of chronic beryllium disease.

@article{Samuel2008ImmunologyOC,
  title={Immunology of chronic beryllium disease.},
  author={George Samuel and Lisa A Maier},
  journal={Current opinion in allergy and clinical immunology},
  year={2008},
  volume={8 2},
  pages={
          126-34
        }
}
PURPOSE OF REVIEW This review discusses the immunology of chronic beryllium disease. It addresses the importance of the interaction between class II molecules and the T cells that recognize beryllium, along with the subsequent immune response that results in sensitization and disease, and genetic factors leading to variation in this response. RECENT FINDINGS HLA-DPB1 with a glutamic acid at amino acid position 69 (Glu69) confers increased risk of beryllium sensitization and is not specific… CONTINUE READING
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