Immunology of Thyroid Eye Disease : New Treatments on the Horizon ?

Abstract

GD is an autoimmune disease where circulating antibodies cause hyperthyroidism and lead to thyrotoxicosis. These antibodies, originally referred to as long-acting thyroid stimulators, are directed against the thyrotropin receptor (TSHR). They mimic the agonist activity of TSH but are not subject to the normal feedback in the anterior pituitary. GD is… (More)

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