Immunology and immunotherapy of Alzheimer's disease

@article{Weiner2006ImmunologyAI,
  title={Immunology and immunotherapy of Alzheimer's disease},
  author={Howard L. Weiner and Dan Frenkel},
  journal={Nature Reviews Immunology},
  year={2006},
  volume={6},
  pages={404-416}
}
Although Alzheimer's disease is considered to be a degenerative brain disease, it is clear that the immune system has an important role in the disease process. As discussed in this Review, immune-based therapies that are designed to remove amyloid-β peptide from the brain have produced positive results in animal models of the disease and are being tested in humans with Alzheimer's disease. Although immunotherapy holds great promise for the treatment of Alzheimer's disease, clinical trials of… CONTINUE READING
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Anti - A β 42and antiA β 40specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model

  • Y. Levites
  • J . Clin . Invest .
  • 2005

Evaluation of the safety and immunogenicity of synthetic A β 42 ( AN 1792 ) in patients with AD

  • A. J. Bayer
  • Neurology
  • 2005

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