Immunologically-mediated restraint of latent tumour metastases

@article{Eccles1975ImmunologicallymediatedRO,
  title={Immunologically-mediated restraint of latent tumour metastases},
  author={Suzanne A. Eccles and P. Hansen Alexander},
  journal={Nature},
  year={1975},
  volume={257},
  pages={52-53}
}
DIFFERENT grafted sarcomas, all originally from chemically-induced autochthonous tumours, vary widely in their capacity to form metastases, as determined by the incidence of secondaries which appear in the lung and lymph nodes in the months following surgical removal of the ‘primary’ transplant from syngeneic rats1. Tumours which do not form metastases readily in normal animals can be induced to do so by grafting into syngeneic rats depleted of T lymphocytes by procedures which do not… CONTINUE READING
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