Immunological suppression by human CD8+ T cells is receptor dependent and HLA-DQ restricted.

Abstract

Mechanisms of specific immunologic unresponsiveness or tolerance and their regulation by the major histocompatibility complex remain central issues in immunology. Recent findings that potentially reactive anti-self T cells are not completely clonally deleted in the thymus and that specific immunological unresponsiveness can be acquired in certain infectious… (More)

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