Immunological roles of Pasteurella multocida toxin (PMT) using a PMT mutant strain.

@article{Kim2007ImmunologicalRO,
  title={Immunological roles of Pasteurella multocida toxin (PMT) using a PMT mutant strain.},
  author={Tae Jung Kim and Nguyen Tat Toan and Eun Jin Jang and Bock Gie Jung and Jae il Lee and Bong Joo Lee},
  journal={Journal of microbiology},
  year={2007},
  volume={45 4},
  pages={364-6}
}
The immunological role of the Pasteurella multocida toxin (PMT) in mice was examined using a PMT mutant strain. After a nasal inoculation, the mutant strain failed to induce interstitial pneumonia. Moreover, PMT had no significant effect on the populations of CD4+, CD8+, CD3+, and CD19+ immunocytes in blood or on the populations of CD4+ and CD8+ splenocytes (P<0.01). However, there was a significant increase in the total number of cells in the BAL samples obtained from the wild-type P… CONTINUE READING