Immunological properties of umbilical cord blood-derived mesenchymal stromal cells.

@article{Oh2008ImmunologicalPO,
  title={Immunological properties of umbilical cord blood-derived mesenchymal stromal cells.},
  author={Wonil Oh and D S Kim and Yoon Sun Yang and Jae Kwon Lee},
  journal={Cellular immunology},
  year={2008},
  volume={251 2},
  pages={116-23}
}
Mesenchymal stromal cells (MSCs) are promising candidates for developing cell therapies for intractable diseases. To assess the feasibility of transplantation with human umbilical cord blood (hUCB)-derived MSCs, we analyzed the ability of these cells to function as alloantigen-presenting cells (APC) in vitro. hUCB-MSCs were strongly positive for MSC-related antigens and stained positively for human leukocyte antigen (HLA)-AB and negatively for HLA-DR. When treated with interferon (IFN)-gamma… CONTINUE READING