Immunological properties of a fusion protein containing nucleocapsid protein and glycoprotein Gn of Hantaan virus.

Escherichia coli and the baculovirus Bac-to-Bac system were used to express chimeric gene GnS0.7 consisting of glycoprotein Gn gene and the 0.7 kb fragment of S genome segment carrying nucleoprotein (N) gene of Hantaan virus (HTNV). The expressed fusion protein GnN0.7 was recognized by monoclonal antibodies (MAbs) to HTNV Gn glycoprotein and N protein… CONTINUE READING