Immunological profiling of tuberculosis-associated immune reconstitution inflammatory syndrome and non-immune reconstitution inflammatory syndrome death in HIV-infected adults with pulmonary tuberculosis starting antiretroviral therapy: a prospective observational cohort study.

@article{Ravimohan2015ImmunologicalPO,
  title={Immunological profiling of tuberculosis-associated immune reconstitution inflammatory syndrome and non-immune reconstitution inflammatory syndrome death in HIV-infected adults with pulmonary tuberculosis starting antiretroviral therapy: a prospective observational cohort study.},
  author={Shruthi Ravimohan and Neo Tamuhla and Andrew P. Steenhoff and Rona Letlhogile and Kebatshabile Nfanyana and Scarlett L. Bellamy and R Ob Roy Macgregor and Robert Gross and Drew Weissman and Gregory P. Bisson},
  journal={The Lancet. Infectious diseases},
  year={2015},
  volume={15 4},
  pages={
          429-38
        }
}
BACKGROUND Patients co-infected with advanced HIV and tuberculosis are at risk of tuberculosis-associated immune reconstitution inflammatory syndrome (IRIS) and death soon after initiation of antiretroviral therapy (ART). Tuberculosis-associated IRIS has been associated with quicker recovery of cellular immune responses after ART initiation and early mortality with slower recovery of these responses. We aimed to assess whether patients who have these outcomes have distinct immunological… CONTINUE READING
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