Immunological microenvironments in the human vagina and cervix: mediators of cellular immunity are concentrated in the cervical transformation zone.

@article{Pudney2005ImmunologicalMI,
  title={Immunological microenvironments in the human vagina and cervix: mediators of cellular immunity are concentrated in the cervical transformation zone.},
  author={Jeffrey Pudney and Alison J Quayle and Deborah Jean Anderson},
  journal={Biology of reproduction},
  year={2005},
  volume={73 6},
  pages={1253-63}
}
Cell-mediated immunity (CMI) is key to defense against intracellular pathogens such as Chlamydia trachomatis and viruses that infect the lower female genital tract, but little is known about CMI at this site. Recent studies indicate that there are immunological microenvironments within the female genital tract, and that immune functions are affected by hormones as well as infections and inflammatory processes. To determine the distribution of mediators of CMI within the lower female genital… CONTINUE READING

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