Immunological methods to quantify and characterize proteasome complexes: development and application.

Abstract

The ubiquitin-proteasome pathway plays major roles in all aspects of biology and contributes to various disease processes. Due to the lack of assays that permit proteasome quantification in crude cell extracts, its concentrations in health and disease states as well as the relationship between free 20S core particles (20S) and 26S proteasomes (26S) that… (More)
DOI: 10.1016/j.jim.2008.02.004

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