Immunological functions of hyaluronan and its receptors in the lymphatics.

@article{Jackson2009ImmunologicalFO,
  title={Immunological functions of hyaluronan and its receptors in the lymphatics.},
  author={David M. Jackson},
  journal={Immunological reviews},
  year={2009},
  volume={230 1},
  pages={216-31}
}
The lymphatic system is best known for draining interstitial fluid from the tissues and returning it to the blood circulation. However, the lymphatic system also provides the means for immune surveillance in the immune system, acting as conduits that convey soluble antigens and antigen-presenting cells from the tissues to the lymph nodes, where primary lymphocyte responses are generated. One macromolecule that potentially unites these two functions is the large extracellular matrix… CONTINUE READING