Immunological evaluation of the mycotoxin patulin in female B6C3F1 mice.

  title={Immunological evaluation of the mycotoxin patulin in female B6C3F1 mice.},
  author={Gerald C. Llewellyn and J. Ann McCay and Ronnetta D. Brown and Deborah L Musgrove and Leon F Butterworth and Albert E. Munson and Kimber L. White},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  volume={36 12},
Patulin is a mycotoxin produced by many fungal species of the genera Penicillium, Aspergillus and Bryssochamys. Previous literature reports have suggested that patulin is toxic to the immune system. The studies presented were conducted to provide a comprehensive assessment of the effects of patulin on the immune system. Unlike previous reports, the doses of patulin used (0.08, 0.16, 0.32, 0.64, 1.28 and 2.56 mg/kg) were based on predicted human exposure levels. Female B6C3F1 mice were exposed… CONTINUE READING
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