Immunological effects and tolerability of a new fast updosed immunologically enhanced subcutaneous immunotherapy formulation with optimized allergen/adjuvant ratio.

@article{Pfaar2012ImmunologicalEA,
  title={Immunological effects and tolerability of a new fast updosed immunologically enhanced subcutaneous immunotherapy formulation with optimized allergen/adjuvant ratio.},
  author={Oliver Pfaar and K K Jung and Hendrik Wolf and Elke Decot and Joerg Kleine-Tebbe and L Klimek and Eike Gunther W{\"u}stenberg},
  journal={Allergy},
  year={2012},
  volume={67 5},
  pages={630-7}
}
BACKGROUND Subcutaneous immunotherapy (SCIT) traditionally includes an updosing phase injecting increasing doses of allergen over a period of several weeks, followed by a maintenance phase. To establish shorter and more convenient updosing schedules, a fast updosed immunologically enhanced SCIT formulation has been developed by optimizing the allergen/adjuvant (aluminium hydroxide) ratio. METHODS In a randomized, controlled, parallel-group trial, patients with grass pollen induced… CONTINUE READING
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