Immunological defense mechanisms in tuberculosis and MAC-infection.

  title={Immunological defense mechanisms in tuberculosis and MAC-infection.},
  author={Pia Hartmann and Georg Plum},
  journal={Diagnostic microbiology and infectious disease},
  volume={34 2},
Protective immunity to mycobacterial infections develops in immunocompetent hosts after activation of alpha beta- and gamma delta-T cells in association with the generation of a protection-specific cytokine profile that stimulates the bactericidal potential of the macrophages. The maintenance of a delicate balance between Th1 and Th2 response is decisive for infection control and prevention of exacerbation of disease. Mycobacterial infection in the immunocompromised host is mainly due to the… CONTINUE READING


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