Immunological crossreactivity of the Mycobacterium leprae CFP-10 with its homologue in Mycobacterium tuberculosis.

@article{Geluk2004ImmunologicalCO,
  title={Immunological crossreactivity of the Mycobacterium leprae CFP-10 with its homologue in Mycobacterium tuberculosis.},
  author={Annemieke Geluk and Krista E van Meijgaarden and Kees L M C Franken and Brigitte Wieles and Sandra M. Arend and W. Faber and Bernard Naafs and Tom Henricus Maria Ottenhoff},
  journal={Scandinavian journal of immunology},
  year={2004},
  volume={59 1},
  pages={66-70}
}
Mycobacterium tuberculosis culture filtrate protein-10 (CFP-10) (Rv3874) is considered a promising antigen for the immunodiagnosis of tuberculosis (TB) together with early secreted antigens of M. tuberculosis (ESAT-6). Both ESAT-6 and CFP-10 are encoded by the RD1 region that is deleted from all tested M. bovis bacille Calmette-Guérin (BCG) strains but present in M. leprae, M. tuberculosis, M. bovis, M. kansasii, M. africanum and M. marinum. In this study, the homologue of CFP-10 in M. leprae… CONTINUE READING
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