Immunological comparison of scrapie-associated fibrils isolated from animals infected with four different scrapie strains.

@article{Kascsak1986ImmunologicalCO,
  title={Immunological comparison of scrapie-associated fibrils isolated from animals infected with four different scrapie strains.},
  author={R. Kascsak and R. Rubenstein and P. Merz and R. Carp and N. Robakis and H. Wiśniewski and H. Diringer},
  journal={Journal of virology},
  year={1986},
  volume={59 3},
  pages={
          676-83
        }
}
Scrapie-associated fibrils (SAFs) are abnormal filamentous structures that are uniquely associated with unconventional slow virus diseases. The antigenic relationships of SAFs from animals infected with four biologically distinct scrapie strains were investigated by using antisera raised to purified SAF proteins. Rabbit antisera were raised to SAFs isolated from mice infected with the ME7 scrapie strain and to SAFs isolated from hamsters infected with the 263K scrapie strain. A strong antigenic… Expand
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