Immunological characterization of the early human fracture hematoma.

@article{Hoff2016ImmunologicalCO,
  title={Immunological characterization of the early human fracture hematoma.},
  author={Paula Hoff and Timo Gaber and Cindy Strehl and Kate Schmidt-Bleek and Annemarie Lang and D{\"o}rte Huscher and Gerd ‐ R{\"u}diger Burmester and Gerhard Schmidmaier and Carsten Perka and Georg N. Duda and Frank Buttgereit},
  journal={Immunologic research},
  year={2016},
  volume={64 5-6},
  pages={1195-1206}
}
The initial inflammatory phase of fracture healing is of great importance for the clinical outcome. We aimed to develop a detailed time-dependent analysis of the initial fracture hematoma. We analyzed the composition of immune cell subpopulations by flow cytometry and the concentration of cytokines and chemokines by bioplex in 42 samples from human fractures of long bones <72 h post-trauma. The early human fracture hematoma is characterized by maturation of granulocytes and migration of… CONTINUE READING

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