Immunological aspects of allogeneic and autologous mesenchymal stem cell therapies.


Mesenchymal stem cells (MSCs) have potential for therapeutic application as an immunomodulatory and regenerative agent. The immunogenicity and survival of MSCs after infusion are, however, not clear and evidence suggests that allogeneic but also autologous MSCs disappear rapidly after infusion. This may be associated with the susceptibility of MSCs to lysis… (More)
DOI: 10.1089/hum.2011.039