Immunological and clinical differences between juvenile and adult onset of systemic lupus erythematosus.

@article{Carreo1999ImmunologicalAC,
  title={Immunological and clinical differences between juvenile and adult onset of systemic lupus erythematosus.},
  author={Luis Carre{\~n}o and Francisco Javier L{\'o}pez-Longo and Indalecio Monteagudo and Margarita Rodr{\'i}guez-Mahou and Marta B{\'a}scones and Carlos M. Gonzalez and Claire Saint-Cyr and Normand D Lapointe},
  journal={Lupus},
  year={1999},
  volume={8 4},
  pages={287-92}
}
INTRODUCTION Systemic lupus erythematosus (SLE) in children usually follows a more severe course than in adults, but sometimes in the previous studies reported there are many confounding factors. OBJECTIVE To analyse the immunological and clinical characteristics of SLE juvenile onset and SLE adult onset. METHODS We studied 179 patients with SLE, 49 patients were aged 6-18 yrs at onset of disease. Anti-dsDNA antibodies were detected by radioimmunoassay and antibodies to extractable nuclear… CONTINUE READING

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