Immunological Properties of Trehalose Dimycolate (Cord Factor) and Other Mycotic Acid‐Containing Glycolipids–‐A Review

@article{Ryll2001ImmunologicalPO,
  title={Immunological Properties of Trehalose Dimycolate (Cord Factor) and Other Mycotic Acid‐Containing Glycolipids–‐A Review},
  author={R. Ryll and Y. Kumazawa and I. Yano},
  journal={Microbiology and Immunology},
  year={2001},
  volume={45}
}
  • R. Ryll, Y. Kumazawa, I. Yano
  • Published 2001
  • Biology, Medicine
  • Microbiology and Immunology
  • Mycolic acids are characteristic fatty acids of Mycobacteria and are responsible for the wax‐like consistence of these microorganisms. Decades of research revealed that mycolic acid‐containing glycolipids, in particular trehalose‐6,6′‐dimycolate (TDM, cord factor) as their best‐studied representative, exert a number of immunomodifying effects. They are able to stimulate innate, early adaptive and both humoral and cellular adaptive immunity. Most functions can be associated with their ability to… CONTINUE READING
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