Immunological Demyelination Triggers Macrophage/Microglial Cells Activation without Inducing Astrogliosis

Abstract

The glial scar formed by reactive astrocytes and axon growth inhibitors associated with myelin play important roles in the failure of axonal regeneration following central nervous system (CNS) injury. Our laboratory has previously demonstrated that immunological demyelination of the CNS facilitates regeneration of severed axons following spinal cord injury… (More)
DOI: 10.1155/2013/812456

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