Immunologic variables in acute mania of bipolar disorder

  title={Immunologic variables in acute mania of bipolar disorder},
  author={Hsing-cheng Liu and Yi-yuan Yang and Yech-Mei Chou and Kun-Po Chen and Sy-Jye Leu},
  journal={Journal of Neuroimmunology},
Macrophages, lymphocytes and their products, may be involved in the pathophysiology of psychiatric disorders. The cell-mediated immune activation response of manic patients during pre-medication and medication stages remains unclear. The purpose of this case-control study was to investigate the plasma levels of immunologic variables, including interleukin (IL)-1 receptor antagonist (IL-1RA), soluble CD 4 (sCD4) and sCD8, and TH1 (interferon [IFN]-gamma and IL-2) and TH2 (IL-4 and IL-10… CONTINUE READING

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