Immunologic therapy of multiple sclerosis.

  title={Immunologic therapy of multiple sclerosis.},
  author={Barry G. W. Arnason},
  journal={Annual review of medicine},
Three interferon beta preparations (Betaseron, Avonex, and Rebif) have shown efficacy in the treatment of relapsing-remitting multiple sclerosis (MS). Attack frequency is reduced by 30% and major attacks to an even greater extent. Accumulating disease burden as measured by annual T2-weighted magnetic resonance imaging is markedly lessened, and disease activity as measured by serial gadolinium-enhanced MRI scanning is reduced by over 80%. A fourth preparation, Copaxone, a basic copolymer of four… CONTINUE READING

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