Immunologic sensitization in recipients of left ventricular assist devices.

  title={Immunologic sensitization in recipients of left ventricular assist devices.},
  author={Ranjit John and Katherine Lietz and Michael Schuster and Yoshifumi Naka and Vivek Rao and Donna M. Mancini and E. A. Rose and Craig R Smith and Mehmet C. Oz and Niloo M. Edwards and Silviu Itescu},
  journal={The Journal of thoracic and cardiovascular surgery},
  volume={125 3},
OBJECTIVE Left ventricular assist device implantation is associated with an increased risk of development of circulating anti-HLA class I and II antibodies (sensitization). We investigated the impact of sensitization on posttransplantation outcomes in 105 consecutive left ventricular assist device recipients. METHODS Five hundred twenty-one consecutive adult cardiac allograft recipients between 1992 and 1999 were retrospectively studied. Of these, 105 were supported with a left ventricular… CONTINUE READING


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