Immunologic risk factors and glomerular C4d deposits in chronic transplant glomerulopathy.

@article{Sijpkens2004ImmunologicRF,
  title={Immunologic risk factors and glomerular C4d deposits in chronic transplant glomerulopathy.},
  author={Yvo W. J. Sijpkens and Simone A Joosten and Man-Chi Wong and Friedo Wilhelm Dekker and Hallgrimur Benediktsson and Ingeborg M. Bajema and Jan Anthonie Bruijn and Leendert C. Paul},
  journal={Kidney international},
  year={2004},
  volume={65 6},
  pages={
          2409-18
        }
}
BACKGROUND Chronic transplant glomerulopathy is an uncommon cause of chronic transplant dysfunction of unknown pathogenesis. We evaluated the epidemiologic, clinical, and histologic features of chronic transplant glomerulopathy. To determine the possible contribution of humoral immune responses, we assessed glomerular deposition of C4d. METHODS From a cohort of 1111 kidney transplants (1983 to 2001) with at least 6 months of graft function, we identified 18 cases with chronic transplant… CONTINUE READING

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CITES BACKGROUND

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