Immunologic response to cryoablation of breast cancer

  title={Immunologic response to cryoablation of breast cancer},
  author={Michael S Sabel and Matthew A. Nehs and Gang Su and Kathleen P. Lowler and James L. M. Ferrara and Alfred E. Chang},
  journal={Breast Cancer Research and Treatment},
Purpose.With improvements in breast imaging and image-guided interventions, there is interest in ablative techniques for breast cancer. Cryosurgery initiates inflammation and leaves tumor-specific antigens intact, which may induce an anti-tumor immune response. To help define the mechanisms involved in the cryoimmunologic response, we compared cryosurgery to surgery in a murine model of breast cancer. Experimental designBALB/c mice with MT-901 tumors underwent cryoablation or resection. Mice… CONTINUE READING


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