Immunologic diagnosis of alpha-thalassemia traits.

Abstract

Frequently it is impossible to diagnose alpha-thalassemia-2 trait from hematologic findings, since the red cell morphology and the MCV are normal. In such cases, after the neonatal period Hb Bart's is not detectable by conventional electrophoreses and chromatography. Antibody against Hb Bart's was produced in rabbits by repeated injections with Hb Bart's… (More)

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