Immunologic analysis of mononuclear cells in liver tissues and blood of patients with primary sclerosing cholangitis.

@article{Whiteside1985ImmunologicAO,
  title={Immunologic analysis of mononuclear cells in liver tissues and blood of patients with primary sclerosing cholangitis.},
  author={Theresa L Whiteside and Steve S Lasky and Lusheng Si and David H. van Thiel},
  journal={Hepatology},
  year={1985},
  volume={5 3},
  pages={468-74}
}
Using monoclonal antibodies to surface antigens, we typed and quantitated the mononuclear cells (MNCs) infiltrating liver tissues from 23 patients with primary sclerosing cholangitis. The circulating T lymphocytes were also enumerated by flow cytometry in 12 of these patients. In blood, T lymphocytes and especially T8+ cells were decreased. T cells were the major components of MNCs (78%) in portal tracts. Few of these cells were Tac+ or HLA-DR+. Total MNCs (929 +/- 90 vs. 106 +/- 18 in controls… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

The immunology of primary sclerosing cholangitis

Springer Seminars in Immunopathology • 1990
View 4 Excerpts
Highly Influenced

Pathogenesis of primary sclerosing cholangitis

Best practice & research. Clinical gastroenterology • 2011
View 1 Excerpt

Similar Papers

Loading similar papers…