Immunologic analysis of cerebrospinal fluid lymphocytes in Vogt-Koyanagi-Harada disease.

  title={Immunologic analysis of cerebrospinal fluid lymphocytes in Vogt-Koyanagi-Harada disease.},
  author={Kazumi Norose and Akiko Yano and Fumie Aosai and Kayoko Segawa},
  journal={Investigative ophthalmology & visual science},
  volume={31 7},
In this study, we focused upon the immunologic aspects of Vogt-Koyanagi-Harada disease (VKH) by comparing the cytotoxic activity of peripheral blood leukocytes (PBL) to that of cerebrospinal fluid leukocytes (CSFL) against the human melanoma cell line (P-36) and the human cervical carcinoma cell line (HeLa-S3). The PBL from patients with VKH showed significant cytotoxic activity against P-36 (P less than 0.01), but did not show cytotoxic activity against HeLa-S3. The CSFL showed significantly… CONTINUE READING


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