Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.

@article{Garcia2004ImmunolocalizationOT,
  title={Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.},
  author={Kelly Garcia and Tanvi Shah and Jesus Garcia},
  journal={American journal of physiology. Cell physiology},
  year={2004},
  volume={287 4},
  pages={C1048-57}
}
The precise localization and role of inositol 1,4,5-trisphosphate (InsP(3)) receptors (InsP(3)Rs) in cardiac muscle cells are largely unknown. It is believed that waves and oscillations in cytosolic free calcium triggered by activation of InsP(3)Rs underlie modifications of cellular responses that lead to changes in gene expression in other cells. However, how changes in cytosolic calcium alter gene expression in cardiac cells is unknown. Moreover, it is unclear how changes in cytosolic calcium… CONTINUE READING

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Depolarization-induced slow calcium C1055 LOCALIZATION AND FUNCTION OF TYPE 2 INSP3R IN CARDIOCYTES AJP-Cell Physiol

  • MA Carrasco, N Riveros, +5 authors E. Jaimovich
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