Immunolocalization of tissue inhibitor of metalloproteinases-1 within ovine periovulatory follicular and luteal tissues.

@article{McIntush1996ImmunolocalizationOT,
  title={Immunolocalization of tissue inhibitor of metalloproteinases-1 within ovine periovulatory follicular and luteal tissues.},
  author={Eric W. McIntush and J D Pletz and Gary Daniel Smith and Denise K Long and Heywood R. Sawyer and Michael Smith},
  journal={Biology of reproduction},
  year={1996},
  volume={54 4},
  pages={871-8}
}
In previous studies, tissue inhibitor of metalloproteinases (TIMP)-1 mRNA increased in follicular tissue after the preovulatory gonadotropin surge and was expressed in luteal tissue. However, the localization of TIMP-1 protein within ovine periovulatory follicular and luteal tissues is unknown. The objectives of the present study were to 1) localize TIMP-1 within follicles collected before and after a preovulatory gonadotropin surge and within Day 3 and Day 10 corpora lutea (CL), 2) determine… CONTINUE READING