Immunolocalization of the proton-coupled oligopeptide transporter PEPT2 in developing rat brain.

  title={Immunolocalization of the proton-coupled oligopeptide transporter PEPT2 in developing rat brain.},
  author={Hong Shen and David E Smith and Richard F. Keep and Frank C. Brosius},
  journal={Molecular pharmaceutics},
  volume={1 4},
This study examined the tissue distribution, cellular localization, and developmental expression of the PEPT2 protein in rat brain. Immunoblot and immunocytochemistry analyses were performed with specific rat PEPT1 and PEPT2 antisera developed in our laboratory. Rats were examined from fetus (gestation for 17 days) to adult (day 75). On immunoblot analysis, the PEPT2 protein was detected in cerebral cortex, olfactory bulb, basal ganglia, cerebellum, and hindbrain sections of adult brain, with… CONTINUE READING


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