Immunolocalization of surfactant protein-D (SP-D) in human fetal, newborn, and adult tissues.

@article{Stahlman2002ImmunolocalizationOS,
  title={Immunolocalization of surfactant protein-D (SP-D) in human fetal, newborn, and adult tissues.},
  author={Mildred T. Stahlman and Mary Ellen Gray and William M. Hull and Jeffrey A. Whitsett},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={2002},
  volume={50 5},
  pages={651-60}
}
Immunoreactive surfactant protein-D (SP-D) was assessed in human fetal, newborn, and adult tissues. In the fetal lung, SP-D was detected on airway surfaces by 10 weeks' gestation, staining increasing in the distal airways, decreasing in the proximal conducting airways with advancing gestation. In lungs from near-term infants and adults, SP-D was detected in Type II cells, serous cells of tracheobronchial glands, and subsets of cells lining peripheral airways. Immunostaining was decreased or… CONTINUE READING