Immunolocalization of scrapie amyloid in non-congophilic, non-birefringent deposits in golden Syrian hamsters with experimental transmissible mink encephalopathy.

@article{Guiroy1993ImmunolocalizationOS,
  title={Immunolocalization of scrapie amyloid in non-congophilic, non-birefringent deposits in golden Syrian hamsters with experimental transmissible mink encephalopathy.},
  author={Don C. Guiroy and Richard F. Marsh and Ryoji Yanagihara and D. Carleton Gajdusek},
  journal={Neuroscience letters},
  year={1993},
  volume={155 1},
  pages={112-5}
}
Transmissible mink encephalopathy (TME), a naturally occurring subacute spongiform encephalopathy in commercially ranch-reared mink (Mustela vision), is characterized neuropathologically by spongiform changes in the neuropil, intracytoplasmic neuronal vacuolation and astrocytic hypertrophy and hyperplasia. Amyloid deposits have not been observed in brain tissue sections from animals with natural and experimental TME using conventional histochemical stains such as Congo red. To determine if… CONTINUE READING