Immunolocalization of NK-1 receptor and Substance P in human normal placenta.

  title={Immunolocalization of NK-1 receptor and Substance P in human normal placenta.},
  author={Miguel Bethencourt Mu{\~n}oz and Antonio Pav{\'o}n and Marisa Rosso and Mar{\'i}a V. Salinas and Ana Isabel Padilla P{\'e}rez and Andr{\'e}s Carranza and Ana Gonz{\'a}lez-Ortega},
  volume={31 7},
A role for Substance P (SP) in human placenta is not known, although is possible that regulates placental physiology through the Neurokinin (NK)-1 receptor. Ten human normal placenta tissues were studied by immunohistochemistry to demonstrate the localization of NK-1 receptor and SP. An immunostaining pattern for NK-1 receptor and SP was observed in the endothelium and myocytes of fetal blood vessels, decidua and trophoblast. The SP is located in both the cytoplasm and the nucleus whereas NK-1… CONTINUE READING
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