Immunolocalization of 3 beta-hydroxysteroid dehydrogenase in human ovary.

  title={Immunolocalization of 3 beta-hydroxysteroid dehydrogenase in human ovary.},
  author={Hisanobu Sasano and Takahide Mori and Nobuaki Sasano and Hiroshi Nagura and James Ian Mason},
  journal={Journal of reproduction and fertility},
  volume={89 2},
Immunohistochemical localization of 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) was performed in 55 cases of morphologically normal human ovaries by using a specific polyclonal antibody against purified human placental 3 beta-HSD. In small developing follicles, immunoreactivity was observed only in the theca interna but also became recognizable in the membrana granulosa with development of the follicle. At a late stage of folliculogenesis, the intensity of the 3 beta-HSD activity in the… CONTINUE READING
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