Immunolocalization and characterization of cornification proteins in snake epidermis.

@article{Alibardi2005ImmunolocalizationAC,
  title={Immunolocalization and characterization of cornification proteins in snake epidermis.},
  author={Lorenzo Alibardi and Mattia Toni},
  journal={The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology},
  year={2005},
  volume={282 2},
  pages={
          138-46
        }
}
Little is known about specific proteins involved in keratinization of the epidermis of snakes, which is composed of alternating beta- and alpha-keratin layers. Using immunological techniques (immunocytochemistry and immunoblotting), the present study reports the presence in snake epidermis of proteins with epitopes that cross-react with certain mammalian cornification proteins (loricrin, filaggrin, sciellin, transglutaminase) and chick beta-keratin. alpha-keratins were found in all epidermal… CONTINUE READING