Immunohistological study of precancerous mucus modification in human distal colonic polyps.

  title={Immunohistological study of precancerous mucus modification in human distal colonic polyps.},
  author={Jacques Bara and O. Languille and Martin Gendron and Noha Daher and Emmanuel Martin and Pascal Burtin},
  journal={Cancer research},
  volume={43 8},
The M1 antigens associated with gastric fucomucins, oncofetal markers of the distal colonic mucosa, were demonstrated to be more closely associated with adenomas [92 of 139 (66%)] than with invasive adenocarcinomas [27 of 218 (12%)]. They were always expressed in tumors containing the M3 antigen normally associated with the intestinal mucus. The M1 antigens, present in 100% of hyperplastic polyps (30 of 30), were not specific for a particular histological type of adenoma but were found to be… CONTINUE READING


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