Immunohistological studies on macrophages in lymph nodes of onchocerciasis patients after treatment with ivermectin.

@article{Knab1997ImmunohistologicalSO,
  title={Immunohistological studies on macrophages in lymph nodes of onchocerciasis patients after treatment with ivermectin.},
  author={Julia Knab and K Darge and Dietrich W. B{\"u}ttner},
  journal={Tropical medicine & international health : TM & IH},
  year={1997},
  volume={2 12},
  pages={1156-69}
}
The role of macrophages in the killing and elimination of microfilariae (mf) was studied immunohistologically in 14 lymph nodes from 10 patients with generalized onchocerciasis 20-68 h after treatment with a single oral dose of 150 microg/kg ivermectin. Mf with signs of damage at light microscopical level were surrounded by a cellular infiltrate comprising macrophages, eosinophils and neutrophils, whereas light microscopically intact mf mostly showed no cellular reaction. Resident mature… CONTINUE READING

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