Immunohistohemical expression of the chemokine fractalkine and its receptor in the human brain cortex after severe traumatic brain injury and brain hemorrhage.

@article{Gaetani2013ImmunohistohemicalEO,
  title={Immunohistohemical expression of the chemokine fractalkine and its receptor in the human brain cortex after severe traumatic brain injury and brain hemorrhage.},
  author={Paolo Gaetani and Patrizia Pisano and Graziella Solinas and Piergiuseppe Colombo and Annarita Destro and Daniel Levi and Enrico Aimar and Ronald Rodr{\'i}guez and Y Baena and Paola Allavena},
  journal={Journal of neurosurgical sciences},
  year={2013},
  volume={57 1},
  pages={55-62}
}
AIM Recent experimental studies have suggested that chemokines, a subclass of chemoattractant cytokines which play an important role in regulating leukocyte migration and intercellular communication, participate in brain responses of traumatic injury. Fractalkine (CX3CL1) is a peculiar chemokine, the only one with a CX3C motif, existing both as a soluble and a membrane-anchored molecule. In the brain, Fractalkine has been suggested to have a role in neuroprotection under experimental conditions… CONTINUE READING
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