Immunohistochemistry of diazepam binding inhibitor (DBI) in the central nervous system and peripheral organs: its possible role as an endogenous regulator of different types of benzodiazepine receptors.

@article{Alho1991ImmunohistochemistryOD,
  title={Immunohistochemistry of diazepam binding inhibitor (DBI) in the central nervous system and peripheral organs: its possible role as an endogenous regulator of different types of benzodiazepine receptors.},
  author={Hannu Alho and T Harjuntausta and R{\"u}diger Schultz and Markku Pelto-Huikko and Patrizia Bovolin},
  journal={Neuropharmacology},
  year={1991},
  volume={30 12B},
  pages={1381-6}
}
The distribution of diazepam binding inhibitor (DBI), a multi-function peptide which has recently been discovered, was studied in the rat and human central nervous system and in peripheral organs of the rat by light and electron microscopical immunohistochemistry. In the central nervous system, DBI-LI was localized in many glial cells and glial tumors, and in some neurons. In the periphery, DBI-LI was found in many tissues but it was expressed selectively in specialized cell types. Intense DBI… CONTINUE READING
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