Immunohistochemistry for histone h3 lysine 9 methyltransferase and demethylase proteins in human melanomas.

Abstract

Methylation and demethylation of histone H3 lysine 9 (H3K9) play a role in the transcriptional regulation of several cancer-related genes and are closely associated with malignant tumor behavior. A novel study has recently demonstrated that SETDB1, a member of the H3K9 methyltransferases, accelerates tumor formation significantly in a zebrafish melanoma… (More)
DOI: 10.1097/DAD.0b013e3182964e02

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@article{Miura2014ImmunohistochemistryFH, title={Immunohistochemistry for histone h3 lysine 9 methyltransferase and demethylase proteins in human melanomas.}, author={Shinpei Miura and Chihaya Maesawa and Masahiko Shibazaki and Shinji Yasuhira and Syuya Kasai and Kanako Tsunoda and Fumihiko Maeda and Kazuhiro Takahashi and Toshihide Akasaka and T. Masuda}, journal={The American Journal of dermatopathology}, year={2014}, volume={36 3}, pages={211-6} }