Immunohistochemically localization of vascular endothelial growth factor, vascular endothelial growth factor receptor-2, collagen I and fibronectin in the epithelia-mesenchymal junction of the human tooth germ.

During tooth development, tooth shape is mediated by the ECM through epithelial-mesenchymal interactions mediated by the ECM at the epithelia-mesenchymal junction. Blood vessel endothelium growth is mainly regulated by vascular endothelial growth factor (VEGF) and the relationship between tooth shape formation and VEGF are unknown. We examined… CONTINUE READING