Immunohistochemically detected expression of Skp2, p27kip1, and p-p27 (Thr187) in patients with cholangiocarcinoma

@article{Luo2015ImmunohistochemicallyDE,
  title={Immunohistochemically detected expression of Skp2, p27kip1, and p-p27 (Thr187) in patients with cholangiocarcinoma},
  author={Jian Luo and Yi Zhou and Bing Wang and Qiang Li and Yongjun Chen and Hongzhen Lan},
  journal={Tumor Biology},
  year={2015},
  volume={36},
  pages={5119-5125}
}
The paper was aimed to detect the expression of Skp2, p27kip1 (p27), and p-p27 (Thr187) in patients with cholangiocarcinoma (CCA). Western blot and immunohistochemistry were used to analyze the expression and subcellular localization of p27, Skp2, and p-p27 (Thr187) in tissue specimens of 53 patients with CCA and 10 with chronic proliferative cholangitis (CPC). Besides, the relationships of p27, Skp2, and p-p27 (Thr187) with clinicopathologic findings were examined, followed by analysis of the… CONTINUE READING