Immunohistochemical study of the expression of cell cycle regulating proteins at different stages of bladder cancer

@article{Primdahl2002ImmunohistochemicalSO,
  title={Immunohistochemical study of the expression of cell cycle regulating proteins at different stages of bladder cancer},
  author={Hanne Primdahl and Hans von der Maase and Flemming Brandt S{\o}rensen and Heinz Wolf and Torben F. {\O}rntoft},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={2002},
  volume={128},
  pages={295-301}
}
AbstractPurpose. The cell cycle is known to be deregulated in cancer. We therefore analyzed the expression of the cell cycle related proteins p21, p27, p16, Rb, and L-myc by immunohistochemical staining of bladder tumors. Methods. The tissue material consisted of bladder tumors from three groups of patients; group 1, 23 patients with recurrent stage Ta (non-invasive) tumors; group 2, 22 patients presenting at their first admission with T2–4 (muscle invasive) tumors; group 3, 24 patients who… CONTINUE READING

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