Immunohistochemical study of the expression of MUC6 mucin and co-expression of other secreted mucins (MUC5AC and MUC2) in human gastric carcinomas.

@article{Reis2000ImmunohistochemicalSO,
  title={Immunohistochemical study of the expression of MUC6 mucin and co-expression of other secreted mucins (MUC5AC and MUC2) in human gastric carcinomas.},
  author={Celso A Reis and Leonor David and Filipa Abreu Gomes de Carvalho and Ulla Mandel and Carme de Bol{\'o}s and Ekaterina Mirgorodskaya and Henrik Clausen and Manuel Sobrinho-Sim{\~o}es},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={2000},
  volume={48 3},
  pages={377-88}
}
To investigate the expression of MUC6 mucin in gastric carcinomas, we generated a novel monoclonal antibody (MAb CLH5) using an MUC6 synthetic peptide. MAb CLH5 reacted exclusively with the MUC6 peptide and with native and deglycosylated mucin extracts from gastric tissues. MAb CLH5 immunoreactivity was observed in normal gastric mucosa restricted to… CONTINUE READING