Immunohistochemical study of nerve fibres in basal cell carcinoma.

  title={Immunohistochemical study of nerve fibres in basal cell carcinoma.},
  author={Ana L Panuncio and Ra{\'u}l A Vignale and Guislena Lopez},
  journal={European journal of dermatology : EJD},
  volume={13 3},
Few studies have been made about the influence of the autonomous nervous system on the proliferation of malignant cells. The aim of this work was to investigate if there is any relationship between the aggressiveness of basal cell carcinoma (BCC) and the presence of nerve fibres. We studied 20 samples of BCC, classified in two groups: non aggressive and aggressive, according to current criteria of malignancy. We used anti-neurofilament (NF) monoclonal antibody and anti-tyrosine hydroxylase (TH… CONTINUE READING