Immunohistochemical study of c-erbB-2 oncoprotein expression in extramammary Paget's disease.

@article{Nishi1994ImmunohistochemicalSO,
  title={Immunohistochemical study of c-erbB-2 oncoprotein expression in extramammary Paget's disease.},
  author={Miyuki Nishi and Hideo Yoshida and Mitsuru Setoyama and Miyuki Tashiro},
  journal={Dermatology},
  year={1994},
  volume={188 2},
  pages={100-2}
}
Sections of formalin-fixed, paraffin-embedded tumor tissue from 20 patients with noninvasive extramammary Paget's disease and 2 patients with invasive extramammary Paget's disease were stained immunohistochemically by means of anti-c-erbB-2 product monoclonal antibody. Membrane staining of intraepidermal tumor cells was found in only 3 of 20 cases of noninvasive extramammary Paget's disease. In the 2 invasive cases, tumor cells of invasive lesions and metastases were positive while… CONTINUE READING